We are using the c5-6 like a baws guide with a couple of variations. Firstly our loki nos's the carrier for extra cap, which relieves the capacitor pressure from the initial archon. Secondly we are slow, sooo slow. If you find us when running a site and are looking to gank us, no need to rush. We will still be there when you get back. Still escalation sites are profitable. I just hope that we pay for our ships before the gankers arive.
I run a C1 -> Highsec PI wormhole, with an open invite policy (please see the recruitment link at the top of the page). I buy PI and haul to market. I still do some PI but not as much myself as I used to with the nullsec market and C5 escalations taking more of my time.
I also run a C2 -> Lowsec/C2 PI wormhole that is pretty quiet at the moment. I recently stuffed up in here ... there were explosions and not of the good kind. I am both incredibly relieved and wildly disappointed that only the ship maintenance arrays showed and dropped loot. The storage and industry arrays array didn't show any loot. That was not from a lack of loot in there.
Unlike in other parts of space, in wormholes I have hunted and ganked pilots and POS alike. Not many, and not often. In wormhole space however, you live and die by the F1 button. If you want a defensive fleet, you will have to bring one. You remain safe in wh space by being belligerent.
I am looking forward to citadels. Assembly of Tech 3 cruisers, sharing space structures with out of corp pilots (friends and alts alike). I have not read but I assume also contracts? I have read that the entirety of the citadel will drop loot. This should encourage more casual ganking of PI holes as there will be (lots more) profitable loot to be gathered. I will have to decide whether to set up medium (3 hour vulnerability per week windows and 'cheap' ) or large (vulnerable twice as long with markets, and so much more expensive) citadels, but no need to decide just yet.
I made my first fortune, as an unskilled newbie, doing wormhole PI. I still spend too much on various projects but ... oh well. I am always recruiting for PI pilots in my wormholes. Whether you are a newbie pilot looking for more than highsec, or a PVP pilot looking to pay for ships, I am recruiting for more PI pilots. If you are interested, please see the recruitment link at the top of the page.