I blame citadel speculation but PI prices are a little out of normal.
Normally P1 ranges from 80 - 700 isk per unit. Today Bacteria (normally 60-80 isk/unit is sitting at 380 isk). Proteins are up to 1100 isk/unit.
P2 normally ranges from 4k isk/unit to 11k isk/unit. today ... Polyaramids are up to 20k isk/unit. (Water Cooled CPU are still aweful)
P3 likewise is now up to 160k isk/unit for High-tech transmitters.
P4, with integrity response drones is up to 3M ISK/unit . Well above the normal 1.3M ISK/unit.
Citadels are coming. The apparent destruction of 120 highsec Poco's from Eve Uni vs Pirat Alts won't help prices come down either.
To see at a glance what is profitable to make at todays prices, use the manufacture tab my Eve PI google doc
To see at a glance what is profitable to extract, use the main tab from the same spreadsheet
I don't often speculate on upcoming patches and still can not tell you if the market is overreacting. What I do know is that I didn't see this price spike for highsec customs offices.